The big picture

Louisville Cardinals are 6–3 in College Football (NCAA) 2026, averaging 40.8 points for and 25.9 against.

Pittsburgh Panthers are 6–3 in College Football (NCAA) 2026, averaging 31.9 points for and 19.8 against.

Form

Louisville Cardinals have won four of their last five and most recently beat Georgia Tech Yellow Jackets 44–17.

Pittsburgh Panthers have won two of their last five and most recently beat Georgia Tech Yellow Jackets 34–11.

Louisville Cardinals arrive on a 4-game winning streak.

Head to head

These sides have met 6 times on our records since 2015: Louisville Cardinals 3, Pittsburgh Panthers 3.

Last time out (2025, Week 5), Louisville Cardinals won 34–27 at Acrisure Stadium.

Biggest margin between these two: Louisville Cardinals by 28 points in 2024 (37–9).

Players to watch

For Louisville Cardinals, watch TJ Quinn (8.3 def total tackles a game in 2023) and Benjamin Perry (4.3 def total tackles a game in 2023).

For Pittsburgh Panthers, watch Donovan McMillon (8.3 def total tackles a game in 2023) and Javon McIntyre (7.7 def total tackles a game in 2023).

At L&N Federal Credit Union Stadium

Louisville Cardinals have won 14 of their last 21 at L&N Federal Credit Union Stadium.

What the numbers say

On form and history, Louisville Cardinals have the edge.