| # | Rider | Time |
|---|---|---|
| 1 | ITAAndrea VendrameDecathlon–AG2R La Mondiale | 6h 28' 25" |
| 2 | GBRTom PidcockQ36.5 Pro Cycling Team | + 0" |
| 3 | FRARomain GrégoireGroupama–FDJ | + 0" |
| 4 | NEDRick PluimersTudor Pro Cycling Team | + 0" |
| 5 | ESPRoger AdriàRed Bull–Bora–Hansgrohe | + 0" |
| 6 | ITASimone VelascoXDS Astana Team | + 0" |
| 7 | ITAFilippo FiorelliVF Group–Bardiani–CSF–Faizanè | + 0" |
| 8 | ESPAlex AranburuCofidis | + 0" |
| 9 | ITASamuele BattistellaEF Education–EasyPost | + 0" |
| 10 | ITAFilippo GannaINEOS Grenadiers | + 0" |
Times in Sydney time (AEDT). Results: Wikipedia, “2025 Tirreno–Adriatico”, CC BY-SA 4.0. Unofficial, updated after the event.