| # | Rider | Time |
|---|---|---|
| 1 | NEDMathieu van der PoelAlpecin–Deceuninck | 6h 22' 53" |
| 2 | ITAFilippo GannaINEOS Grenadiers | + 0" |
| 3 | SLOTadej PogačarUAE Team Emirates XRG | + 0" |
| 4 | AUSMichael MatthewsTeam Jayco–AlUla | + 43" |
| 5 | AUSKaden GrovesAlpecin–Deceuninck | + 43" |
| 6 | DENMagnus CortUno-X Mobility | + 43" |
| 7 | DENMads PedersenLidl–Trek | + 43" |
| 8 | NEDOlav KooijVisma–Lease a Bike | + 43" |
| 9 | ITAMatteo TrentinTudor Pro Cycling Team | + 43" |
| 10 | GBRFred WrightTeam Bahrain Victorious | + 43" |
Times in Sydney time (AEDT). Results: Wikipedia, “2025 Milan–San Remo”, CC BY-SA 4.0. Unofficial, updated after the event.