| # | Rider | Time |
|---|---|---|
| 1 | ITAJonathan MilanLidl–Trek | 4h 45' 13" |
| 2 | NEDMaikel ZijlaardTudor Pro Cycling Team | + 0" |
| 3 | FRAPaul PenhoëtGroupama–FDJ | + 0" |
| 4 | NEDOlav KooijVisma–Lease a Bike | + 0" |
| 5 | ITASimone ConsonniLidl–Trek | + 0" |
| 6 | IRLSam BennettDecathlon–AG2R La Mondiale | + 0" |
| 7 | GBRJake StewartIsrael–Premier Tech | + 0" |
| 8 | NEDTim van DijkeRed Bull–Bora–Hansgrohe | + 0" |
| 9 | FRABryan CoquardCofidis | + 0" |
| 10 | ITAEnrico ZanoncelloVF Group–Bardiani–CSF–Faizanè | + 0" |
Times in Sydney time (AEDT). Results: Wikipedia, “2025 Tirreno–Adriatico”, CC BY-SA 4.0. Unofficial, updated after the event.