The big picture

Houston Texans are 2–5 in NFL 2026, averaging 23.6 points for and 24.3 against.

Indianapolis Colts are 2–6 in NFL 2026, averaging 20.1 points for and 27.8 against.

Form

Houston Texans have won two of their last five and most recently lost to New York Giants 21–27.

Indianapolis Colts have won one of their last five and most recently lost to Jacksonville Jaguars 7–42.

Indianapolis Colts have lost their last four.

Head to head

These sides have met 50 times on our records since 2002: Houston Texans 15, Indianapolis Colts 34, 1 drawn.

Last time out (2026, Week 3), Indianapolis Colts won 19–17 at Lucas Oil Stadium.

Biggest margin between these two: Indianapolis Colts by 35 points in 2004 (49–14).

Players to watch

For Houston Texans, watch Azeez Al-Shaair (9.7 def total tackles a game in 2026) and M.J. Stewart (7.5 def total tackles a game, 1 def sacks in 2026).

For Indianapolis Colts, watch Akeem Davis-Gaither (8.1 def total tackles a game in 2026) and Justin Walley (5 def total tackles a game, 1 def sack in 2026).

At Reliant Stadium

Houston Texans have won 10 of their last 19 at Reliant Stadium.

What the numbers say

On the numbers this is too close to split.