| # | Rider | Time |
|---|---|---|
| 1 | ESPJuan AyusoUAE Team Emirates XRG | 4h 14' 02" |
| 2 | GBRTom PidcockQ36.5 Pro Cycling Team | + 13" |
| 3 | AUSJai HindleyRed Bull–Bora–Hansgrohe | + 13" |
| 4 | ESPMikel LandaSoudal–Quick-Step | + 15" |
| 5 | ITAAntonio TiberiTeam Bahrain Victorious | + 20" |
| 6 | CANDerek GeeIsrael–Premier Tech | + 20" |
| 7 | MEXIsaac del ToroUAE Team Emirates XRG | + 36" |
| 8 | IRLBen HealyEF Education–EasyPost | + 42" |
| 9 | NORTobias Halland JohannessenUno-X Mobility | + 45" |
| 10 | ITALorenzo FortunatoXDS Astana Team | + 50" |
Times in Sydney time (AEDT). Results: Wikipedia, “2025 Tirreno–Adriatico”, CC BY-SA 4.0. Unofficial, updated after the event.